Ozepic, Mounjaro, Wegovy, Semaglutado and Liraglutide. Today most people know what these difficult names mean: they are injectable losses to lose weight available in pens and have brought exceptional results for those who have obesity.
“We had a revolution in the endocrinology area. It began to observe that these remedies really work and, it is, weight loss is higher than the medicines that we used traditionally. Weight loss with these medications reaches up to 20%, in some younger, up to 25%,” explains Paulo Rosenbaum, endocrinologist at Albert Einstein Hospital. He is one of Roberto Kalil’s guests in this Saturday’s Vital Signs, along with Alexandre Azevedo, psychiatrist at the São Paulo Clinic Hospital.
Rosenbaum points, however, two problems: The high cost of medicines (each pen can cost up to R $ 3,000 per month), and indiscriminate use without medical follow -up. “No doubt there is an abuse because it doesn’t need a prescription.”
It is not enough just to lose weight when it comes to obesity
The problem of following without accompaniment is precisely why there is a psychiatrist in this conversation wheel: the emotional impacts of obesity. “We know that 30% of people with obesity have anxiety and depression. Many times these people look for several experts and they arrive at their office already frustrated by the way they were treated, feeling guilty of obesity, ”says Rosenbaum.
“We can reach rates, for example, a prevalence of compulsion disorder of up to 50% in individuals who are in clinical treatment for obesity. And if treatment is not focused for compulsion food disorder, they are individuals who will ‘fail’ in treatment for obesity, increasing frustration,” adds Alexandre Azevedo. “And this question of the cycle of loss and ‘landslides’ (weight) is one of the great factors favoring depression in the individual with obesity.”
Studies show that there are behavioral interventions that may impact the success of weight loss on maintaining this result. This can be as much about the beliefs that people have about some foods and with quality of life guidelines.
Obesity is chronic and multifactorial disease
“We know that there are a number of psychological, biological, hormonal factors that make this person gain weight and have difficulty losing. The big challenge there is the modification of lifestyle,” says Rosenbaum. Therefore, experts advocate an approach not only focused on medicines.
“Restriction diets can have emotional consequences such as depressive symptoms, symptoms of irritability, impatience, insomnia. And then the nutritional guidance comes in, that you don’t have to give up what you like, you can moderate the way you feed on it,” says Azevedo. The psychiatrist points out that sleeping well is a factor that has a direct impact on obesity. “Sleepingly sleeping silently changes the metabolic response, energy expenditure, favoring that an individual gains weight, even if he is not a great eater, even if he does not have an eating disorder, for example.”
Not always thin is the goal of treatment
Azevedo also warns of the importance of aligning expectations. “Sometimes a few words like ‘lose weight’, for example, don’t even fit, because it’s very difficult, depending on an individual’s BMI, he gets thin. So, perhaps the focus are real weight loss goals in which the individual may be satisfied with those achievements and we can value these achievements.”
“We know that 5 to 10% weight loss already shows health and quality of life benefit. So I think it’s up to the endocrinologist or the doctor to put a realistic goal and show the benefits that weight loss will cause.
The “CNN Vital Signs – Dr. Kalil Interview” airs on Saturday, April 5, at 7:30 pm, at CNN Brazil.
This content was originally published in Kalil talks about how injectable pens changed obesity approach on CNN Brazil.
Source: CNN Brasil

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